Compound useful in cholesterol assay procedures

Details Compound useful in cholesterol assay procedures Compound useful in cholesterol assay procedures

1978-10-23

1980-09-23

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603975, C07J 900

Patent

active

042242290

ABSTRACT:
A compound is disclosed herein which is water soluble and is useful in assay procedures for measuring serum cholesterol. In one embodiment, the compound comprises a cholesterol ester having the general formula R.sub.1 --R.sub.2 --[Cholesterol Base], in which R.sub.1 is a water soluble, nonionic surfactant and R.sub.2 is a dicarboxyl group bonded by ester linkages to R.sub.1 and to the cholesterol. In an alternate embodiment the compound comprises a pregnenolone derivative having the general formula R.sub.3 --[Pregnenolone Base]--R.sub.4. A compound in accordance with the present invention is useful by itself or in combination with blood serum as a standard or reference material for cholesterol assay procedues.

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