Compound U-50,228, derivatives thereof, and processes for prepar

Details Compound U-50,228, derivatives thereof, and processes for prepar Compound U-50,228, derivatives thereof, and processes for prepar

1975-10-10

1976-10-26

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

195 80R, 424180, 536 18, C07H 302

Patent

active

039883140

ABSTRACT:
New antiviral agent U-50,228 and derivatives thereof, produced by the controlled fermentation of the known microorganism Streptomyces platensis var. clarensis var nova, NRRL 8035. This antiviral agent and its derivatives are active against DNA-viruses, for example, the Herpes virus and, thus, can be used to control such virus where its presence is not desired. For example, U-50,228 and its derivatives can be used to swab laboratory benches and equipment in a virology laboratory to eliminate the presence of Herpes virus.

REFERENCES:
patent: 3755293 (1973-08-01), Shirato et al.
patent: 3907643 (1975-09-01), DeBoer et al.
patent: 3907779 (1975-09-01), DeBoer et al.
Michelson, "The Chem. of Nucleosides and Nucleotides," Academic Press, New York, N.Y. 1963, pp. 12-14.
Cohn, "J. Biol. Chem." vol. 235, 1960, pp. 1488-1498.
Scannell et al. et al., "Biochim. et. Biophys. Acta." vol. 32, 1959, pp. 409-412.

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