Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-05-26
1996-07-30
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
4352521, 435117, 540495, C07D24310, A61K 3155
Patent
active
055411819
ABSTRACT:
Disclosed is the novel compound BU-4664L and derivatives thereof. The compound is produced by fermentation of Micromonospora sp. M990-6. The compound possesses anti-inflammatory and/or anti-tumor cell activities. BU-4664L has the following structure: ##STR1##
REFERENCES:
patent: 4663347 (1987-05-01), Atkinson et al.
Stephen M. Berge et al., Journal of Pharmaceutical Sciences, "Pharmaceutical Salts", vol. 66, No. 1, pp. 1-19, 1977.
Bengt Samuelsson, Science, "Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation", vol. 220, pp. 568-575, 1983.
J. Orskov, Investigations Into The Morphology of the Ray Fungi, Levin& Munksgaard Publishers, pp. 9-12. 1973.
Derek J. Hook et al., the Journal of Antibiotics, "Identification of the Inhibitory Activity of Carbazomycins B and C Against 5-Lipoxygenase, a A New Activity for These Compounds", vol. XLII, No. 10, pp. 1347-1348, 1990.
The Actinomyceted, vol. II, pp. 328-335. (1957).
E. B. Shirling et al., International Journal of Systematic Bacteriology, "Methods for Characterization of Streptomyces Species", vol. 16, No. 3, pp. 313-340, 1966.
Tadashi Arai., Culture Media for Actinomycetes, "The Society for Actinomycetes", pp. 1-31, 1975.
H. A. Lechevalier et al., A Critical Evaluation of the Genera of Aerobic Actinommycetes, pp. 393-405. 1969.
Joseph L. Staneck et al., Applied Microbiology, "Simplified Approach to Identification of Aerobic Actinomycetes by Thin-Layer Chromatography", vol. 28, No. 2, pp. 226-231, 1974.
Mary P. Lechevalier et al., Biochemical Systematics and Ecology, "Chemotaxonomy of Aerobic Actinomycetes: Phospholipid Composition", vol. 5, pp. 249-260, 1977.
D. E. Minnikin et al., Journal of General Microbiology, "Differentiation of Mycobacterium, Nocardia, and Related Taxa by Thin-Layer Chromatographic Analysis of Whole-Organism Mehtanolysates", vol. 88, pp. 200-204, 1975.
M. D. Collins et al., Journal of Applied Bacteriology, "A Note on the Separation of Natural Mixtures of Bacterial Menquinones Using Reverse Phase Thin-Layer Chromatography", vol. 48, pp. 277-282, 1980.
Ken-Ichiro Suzuki et al., International Journal of Systematic Bacteriology, "Taxonomic Significance of Cellular Fatty Acid Composition in Some Coryneform Bacteria", vol. 33, No. 2, pp. 188-200, 1983.
Anderson Maxwell et al., Journal of Natural Products, "Novel Prenylated Hydroxybenzoic Acid Derivatives From Piper Saltuum", vol. 52, No. 3, pp. 614-618, 1989.
Problems in the Classification of Antagonistic Actinomycetes, published by The American Institute of Biological Sciences, pp. 1-165, 1957.
Anderson Maxwell et al., Journal of Natural Products, "Prenylated 4-Hydroxybenzoic Acid Derivatives From Piper Marginatum", vol. 51, No. 2, pp. 370-373, 1988.
Kazuo Shin-ya et al., Tetrahedron Letters, "The Structure of Benthocyanin A. An New Free Radical Scavenger of Microbial Origin", vol. 32, No. 7, pp. 943-946, 1991.
Kobaru Seikichi
Ohkuma Hiroaki
Berch Mark L.
Bristol--Myers Squibb Company
Savitsky Thomas R.
LandOfFree
Compound produced by a strain of micromonospora does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compound produced by a strain of micromonospora, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compound produced by a strain of micromonospora will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1658707