Compound, oleyl-2-pyridinioethyl phosphate having antifungal and

Details Compound, oleyl-2-pyridinioethyl phosphate having antifungal and Compound, oleyl-2-pyridinioethyl phosphate having antifungal and

1988-09-19

1990-06-19

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548112, 544157, 544159, 544337, C07F 958, C07F 965

Patent

active

049355201

ABSTRACT:
Phospholipids, inclusive of pharmaceutically acceptable salts thereof, of the formula ##STR1## wherein R.sup.1 is a C.sub.8-30 aliphatic hydrocarbon residue, R.sup.2, R.sup.3 and R.sup.4 are independently hydrogen or lower alkyl or ##STR2## represents cyclic ammonio and n is 0 or 1, exhibit inhibitory activity to multiplication of tumor cells and antimycotic (antifungal) and antiprotozoal activities, and are useful for inhibiting multiplication of tumor cells and prolonging the survival time of tumor-bearing warm-blooded animal, for treating or preventing a disease in an animal caused by a mycete (fungus) and for treating or preventing a plant disease.

REFERENCES:
patent: 4426525 (1984-01-01), Hozumi et al.

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