Compound marked with tritium, its preparation and its use in par

Details Compound marked with tritium, its preparation and its use in par Compound marked with tritium, its preparation and its use in par

1989-08-31

1993-03-23

Stoll, Robert L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

424 11, 435 71, 435 723, 435968, C07C 6349, A61K 4902, C07B 5900

Patent

active

051965771

ABSTRACT:
4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl) benzoic acid marked with tritium is used as a radioactive marker in the titration of nuclear receptors and CRABP, in the measurement of the affinity of retinoids for nuclear receptors and CRABP, in the titration of known retinoids, the characterization of antibodies directed against 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl) benzoic acid, and in the study of the distribution and metabolism of said benzoic acid derivative.

REFERENCES:
Dawson et al., J. Med. Chem., vol. 32, pp. 1504-1517, (Jul. 1989).
Dawson et al., J. Labelled Cmpds. Radiopharm., vol. 28, No. 1, pp. 89-98.

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