Compound having vessel smooth muscle relaxation activity

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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540575, 544121, 544130, 544159, 544295, 544362, 544370, 544389, 544391, 544394, 546140, 546149, 546206, 546242, 546338, 548561, 549 75, 549491, C07D40112

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active

050812467

ABSTRACT:
Novel quinoline sulfonamino derivatives having a vessel smooth muscle relaxation activity as well as a platelet agglutination inhibitory activity and inhibitory activity to protein kinase A, myosin light chain kinase, proteinkinase C, and calmodulindependent proteinkinase II, but having little action or cardio function; a process for the production of the derivatives, and a pharmaceutical composition containing the derivative.

REFERENCES:
patent: 4456757 (1984-06-01), Hidaka et al.
patent: 4525589 (1985-06-01), Hidaka et al.
patent: 4560755 (1985-12-01), Hidaka et al.
patent: 4634770 (1987-01-01), Hidaka et al.
patent: 4678783 (1987-07-01), Hidaka et al.
patent: 4709032 (1987-11-01), Hidaka et al.
patent: 4798897 (1989-01-01), Hidaka et al.
Chemical Abstracts 212215 u (1985).
Chemical Abstracts 11096 k (1982).
Chemical Abstracts 37665 v (1987).
Chemical Abstracts, vol. 88(3):22461v, Jan. 16, 1978.

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