Compound having phosphorylcholine group, polymer thereof and...

Details Compound having phosphorylcholine group, polymer thereof and... Compound having phosphorylcholine group, polymer thereof and...

2008-05-27

2008-05-27

Shiao, Rei-Tsang (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

C558S170000, C558S166000

Reexamination Certificate

active

10518462

ABSTRACT:
A compound of the invention is a specific compound having a phosphorylcholine group, and a polymer of the invention comprises at least 1 mol % of repeating units with a phosphorylcholine group and has a number-average molecular weight of 1,000 or more, the repeating units with a phosphorylcholine group being represented by the formula (II):wherein A is a bond selected from a single bond, —O—, —COO—, —OOC—, —CONH—, —NH—, —NHCO—, —NR2— and —CH2O— where R2is an alkyl group having 1 to 6 carbon atoms; and m is an integer of 1 to 12.

REFERENCES:
patent: 5591882 (1997-01-01), Straford et al.
patent: 6040415 (2000-03-01), Arimori et al.
patent: 0574355 (1993-12-01), None
patent: 0767212 (1997-04-01), None
patent: WO 93/01221 (1993-01-01), None
Kazuhiko Ishihara (1999) “New Development of Nonthrombogenic Materials,”Surgery61(2), 4 pages.
Kazuhiko Ishihara (1990) “Preparation of Phospolipid Polymers and Their Properties as Polymer Hydrogel Membranes,”Polymer Journal22(5), pp. 355-360.
Kazuhiko Ishihara (2000) “Bioinspired Phospholipid Polymer Biomaterials for Making High Performance Artificial Organs,”Science and Technology of Advanced Materials I, pp. 131-138.
Kazuhiko Ishihara (2000) “New Polymeric Biomaterials-Phospholipid Polymers with a Biocompatible Surface,”Frontiers Med. Biol. Enging. 10(2), pp. 83-95.
European Search Report mailed on Oct. 12, 2006 for European Patent Application No. EP 04 71 2183. 3 pages.

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