Compound having antitumor activity and process for producing...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C548S453000, C548S512000, C548S544000, C549S548000

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active

RE043038

ABSTRACT:
A compound represented by the general formula (I): (I) wherein R represents linear, branched, or cyclic alkyl or aryl; a process for producing the compound; and an antitumor agent containing the compound as an active ingredient.

REFERENCES:
patent: 8-269061 (1996-10-01), None
Golub et al, Oct. 15, 1999, Science, 286, 531-537.
Hayashi and Narasaka, Chemistry Letters, 1998, pp. 313-314.
Hortobagyi, G., Oct. 1, 1998, N. Engl. J. Med, 339, 974-984.
Kuramochi et al, Tetrahedron Letters, 1999, 40, p. 7371-7374.
Kuramochi et al., Tet. Lett., vol. 40, 1999, 7371-7374, especially p. 7371.
Hayashi et al., Chem Lett., vol. 27(4), 1998, p. 313-314, especially p. 313.
Patani et al., Chem Rev, 1996, vol. 96 (8), especially p. 3147.
Nagumo et al., Bioorganic and Medicinal Chemistry Letters, vol. 14, Iss. 17, 2004, pp. 4425-4429.
Hayashi et al., Chem. Lett., vol. 27(4), 1998, p. 313-314, especially p. 313.
Marumoto et al., “Assymmetric total synthesis of epolactaene”, Yuki Gosel Kagaku Kyokaishi, 2002, vol. 58, No. 3, pp. 183-191.

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