Compound GEX1

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

549414, 549415, 514460, C07D40704, C07D40714, A61K 3135

Patent

active

057191794

ABSTRACT:
Disclosed is Compound GEX1 of formula (I), having excellent antitumor activity: ##STR1## wherein R.sup.1 represents hydroxy or ##STR2## R.sup.2, R.sup.3 and R.sup.4 independently represent hydrogen or hydroxy; R.sup.5 represents hydroxyl or lower alkoxy; provided that when R.sup.1 is hydroxy and R.sup.5 is methoxy, then at least one of R.sup.2, R.sup.3 and R.sup.4 is the group except for hydrogen, and pharmaceutically acceptable salts thereof.

REFERENCES:
The Journal of Antibiotics, vol. 45, No. 6 (Jun. 1992) 914-921.
Journal of Organic Chemistry, vol. 57, No. 26 (Dec. 18, 1992) 7720-26.
Synthesis, vol. 1996, No. 5 (May, 1996) 652-66.

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