Compound for treatment of cardiac arphythmia, synthesis, and met

Details Compound for treatment of cardiac arphythmia, synthesis, and met Compound for treatment of cardiac arphythmia, synthesis, and met

1995-06-06

1998-12-15

Trinh, Ba K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549467, 549468, A61K 3136, C07D30780, C07D30781

Patent

active

058497889

ABSTRACT:
Described is a novel compound and method, useful for treatment of cardiac arrhythmias, especially useful in patients with congestive heart failure (CHF). A process for synthesizing the novel compound is also described.

REFERENCES:
patent: 3248401 (1966-04-01), Tondeur et al.
patent: 4931464 (1990-06-01), Grover et al.
patent: 4962095 (1990-10-01), Grover et al.
patent: 5175187 (1992-12-01), Baligadoo
patent: 5364880 (1994-11-01), Druzgala
patent: 5440054 (1995-08-01), Druzgala
Xu, Yungen et al. (1992) "Synthesis of 3-substituted diiodobenzoylindole derivatives" Chemical Abstracts 116(5):756, abstract No. 41241m.
Bigger, J.T. Jr. (1987) "Why patients with congestive heart failure die: arrhythmias and sudden cardiac death" Circulation 75 (suppl IV):28-35.
Smith, W.M. (1985) "Epidemiology of Congestive Heart Failure" The American Journal of Cardiology 55:3A-8A.
The Cardiac Arrhythmia Supprression Trial (CAST) Investigators (1989) "Preliminary Report: Effect of Encainide and Flecainide on Mortality in a Randomized Trial of Arrhythmia Suppression after Myocardial Infarction" The New England Journal of medicine 321(6):406-412.
Goldstein, S. (1991) "Identification of Patients at Risk for Sudden Death in Congestive Heat Failure" J. Clin. Pharmacol. 31:1085-1088.
McKee, P.A. et al. (1971) "The Natural History of Congestive Heart Failure: The Framingham Study" The New England Journal of Medicine 285(26):1441-1446.
Sami, M.H. (1991) "Sudden Death in Congestive Heart Failure" J. Clin. Pharmacol. 31:1081-1084.

Affiliated with

Also associated with

Rating

Compound for treatment of cardiac arphythmia, synthesis, and met does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compound for treatment of cardiac arphythmia, synthesis, and met, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compound for treatment of cardiac arphythmia, synthesis, and met will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1458462