Compound effective as cerebral insufficiency improver

Details Compound effective as cerebral insufficiency improver Compound effective as cerebral insufficiency improver

1992-11-23

1994-02-22

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

552307, 552309, 552310, 514681, A61K 3121

Patent

active

052887529

ABSTRACT:
A compound having the formula (I): ##STR1## wherein A is --CH.sub.2 --, R.sup.1 is CH.sub.3 or OCH.sub.3 ; R.sup.2 is hydroxy or carboxy, carboxylic acid or carboxylic acid ester group; R.sup.3 is H or a lower alkyl; and n is 0 or an integer of 1 to 6 or a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 4774241 (1988-09-01), Tatsuoka et al.
patent: 5057514 (1991-10-01), Tatsuoka et al.
The Merck Manual, pp. 1336-1340 (1987).
Wauqier, et al. "A New Antihypoxic Drug with Anticonvulsant Properties and Possible Effects on Cognitive Functions," Drug Dev. Res., vol. 8, pp. 373-380 (1986).
Hackinski, et al., "Changing Concepts of Vascular Dementia" Cerebrovascular Diseases, Chapters 20-23, pp. 181-222 (1989).

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