Compound containing a labile disulfide bond

Details Compound containing a labile disulfide bond Compound containing a labile disulfide bond

2006-08-08

2006-08-08

Woitach, Joseph (Department: 1632)

Organic compounds -- part of the class 532-570 series

Organic compounds

Fatty compounds having an acid moiety which contains the...

C435S458000, C424S178100, C424S456000, C514S001000, C514S002600, C514S017400

Reexamination Certificate

active

07087770

ABSTRACT:
A labile disulfide-containing compound under physiological conditions containing a labile disulfide bond and a transduction signal.

REFERENCES:
patent: 5891468 (1999-04-01), Martin et al.
patent: 6025140 (2000-02-01), Langel et al.
patent: 6258774 (2001-07-01), Stein et al.
patent: 6429200 (2002-08-01), Monahan et al.
Normand N, van Leeuwen H, O'Hare P. J Biol Chem. May 4, 2001;276(18):15042-50. Epub Jan. 18, 2001. Particle formation by conserved doamin of the herpes simplex virus protein VP22 facilitating protein and nucleic acid delivery.
Dug Metab Dispos. Jan. 1995;23(1):55-9 Kang YS, Boado RJ, Padridge WM. Pharmacokinetics and organ clearance of a 3′-biotinylated, internally [32P]-labeled phosphodiester oligodeoxynucleotide.
Lee et al. Bioconjugate Chem 2001 12 :995-999.
Moulton et al. Drug Discovery Today 9(20):870.
Arpicco, Silvia, et al., “New Coupling Reagents for the Preparation of Disulfide Cross-Linked Conjugates With Increased Stability.”Bioconjugate Chem.; 1997; vol. 8; pp. 327-337.
Bulaj, Grzegorz, et al., “Ionization-Reactivity Relationships for Cysteine Thiols in Polypeptides.”Biochemistry; 1998; vol. 37; pp. 8965-8972.
Keire, David A., et al., “Kinetics and Equilibria of Thiol/Disulfide Interchange Reactions of Selected Biological Thiols and Related Molecules with Oxidized Glutathione.”J. Org. Chem.; 1992; vol. 57, pp. 123-127.
Keire, David A., et al., “Kinetics and Equilibria of Thiol/Disulfide Interchange Reactions of Selected Biological Thiols and Related Molecules with Oxidized Glutathione.”J. Org. Chem.; 1992, vol. 57, pp. 123-127.
Kishore, K., et al., Polymers Containing Disulfide, Tetrasulfide, Diselenide and Ditelluride Linkages in the Main Chain.Advances in Polymer Sciences; 1995; vol. 121; pp. 83-92.
Lee, Robert J., et al., “Folate-Mediated Tumor Cell Targeting of Liposome-Entrapped Doxorubicin In Vitro.”Biochimica et Biophysica Acta; 1995; vol. 1233, pp. 134-144.
Szajewski, Richard P., et al., “Rate Constants and Equilibrium Constants for Thiol-Disulfide Interchange Reactions Involving Oxidized Glutathione.”Journal of the American Chemical Society; Mar. 12, 1980; vol. 102:6, pp. 2011-2025.
Szajewski, Richard P., et al., “Rate Constants and Equilibrium Constants for Thiol-Disulfide Interchange Reactions Involving Oxidized Glutathione.”Journal of the American Chemical Society; Mar. 12, 1980; vol. 102:6, pp. 2011-2025.
Thorpe, Philip E., et al., “Comparison of Two Anti-Thy 1.1-Abrin A-Chain Immunotoxins Prepared With Different Cross-Linking Agents: Antitumor Effects, In Vivo Fate, and Tumor Cell Mutants.”JNCI; Nov. 1987; vol. 79; No. 5, pp. 1101-1111.
Trubetskoy, Vladimir S., et al., “Quantitative Assessment of DNA Condensation.”Analytical Biochemistry; 1999; vol. 267; pp. 309-313.
Wolff, Jon A., et al., “Direct Gene Transfer Into Mouse Muscle In Vivo.”Science; Mar. 23, 1990; vol. 247; pp. 1465-1468.

Affiliated with

Also associated with

Rating

Compound containing a labile disulfide bond does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compound containing a labile disulfide bond, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compound containing a labile disulfide bond will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3646060