Compositions, uses and methods creating reverse micelles for the

Details Compositions, uses and methods creating reverse micelles for the Compositions, uses and methods creating reverse micelles for the

1982-04-15

1986-08-26

Wiseman, Thomas G.

Chemistry: analytical and immunological testing

Including sample preparation

Digestion or removing interfering materials

436 8, 436 17, 436825, 252351, 252353, 252355, G01N 100, B01F 1700

Patent

active

046083472

ABSTRACT:
Compositions and methods are provided for clarifying and partitioning aqueous lipid-containing specimens or samples such as lipemic serum and plasma. The compositions contain zwitterionic surfactant and water-immiscible organic solvent for lipids. The components of the compositions are selected such that they are compatible in vitro and, when constituted with aqueous specimens, do not interfere with biological or chemical activity of endogenous and exogenous analytes present in the respective specimens. The methods serve to partition the specimens into discrete aqueous and non-aqueous phases. The phases in turn can be individually assayed with respect to any of various analytes, for diagnostic or other purposes.

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