Compositions useful in heterogeneous immunoassays

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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5303913, 5303915, 5303917, 5303919, 436546, 436800, 435 71, 435 792, 435 794, C07K 1600, G01N 33533, G01N 3353

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active

055126596

ABSTRACT:
A method for carrying out an immunoassay for an analyte in which a sample suspected of containing an analyte and reagents useful for detecting the analyte of interest are combined in an aqueous medium, wherein one of the reagents includes a support and one includes a label, the improvement comprising employing as the reagents a first and second conjugate, each comprised of a specific binding pair (sbp) member bound to a small molecule wherein the small molecules of each conjugate are different.

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Neurath, et al., Methods of Enzymology, vol. 73, part B: (J. J. Langone and H. Van Vunakis, editors), pp. 127-138, (1981) "Labeling of Antigens and Antibodies".

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