Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1975-03-03
1976-03-02
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424317, A61K 3119, A61K 31215
Patent
active
039418855
ABSTRACT:
Disclosed herein are compounds of the formula: ##EQU1## wherein Ad is 1-adamantyl; R is H or CH.sub.3 ; X is COOM or CH.sub.2 ##EQU2## wherein M is H or a pharmaceutically acceptable cation, and R.sub.1 is lower n-alkyl; and the pharmaceutically acceptable salts thereof.
Preferred are ethyl-4-[N-(1-adamantyl)-N-methylamino]butyrate, 3-[N-(1-adamantyl-N-methylamino)]propionic acid and their pharmaceutically acceptable salts. These compounds are particularly useful in the treatment of parkinsonism.
Coan Stephen B.
Eisen Bruce M.
Friedman Stanley J.
Schering Corporation
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