Compositions used as a pathological control in a method for the

Details Compositions used as a pathological control in a method for the Compositions used as a pathological control in a method for the

1999-05-21

2000-09-05

Leary, Louise N.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving blood clotting factor

435 4, 435975, 435967, C12Q 156, C12Q 100

Patent

active

061141364

ABSTRACT:
The invention relates to the use of a serum rich in factor Va for the preparation of compositions useful as pathological controls or calibrants in methods for analyzing resistance to activated protein C (APC), as well as said compositions, the method for their preparation and a method for the detection of resistance to activated protein C.

REFERENCES:
Kraus et al.; "Factor V Leiden-Like Behaviour of Animal Plasma and its Use for Calibration of Activated Protein C-Dependent Assays"; Blood Coagulation and Fibrinolysis; vol. 7, No. 3; Apr. 1996; pp. 295-302; XP-002094489.
Le et al; "Blood" vol. 85(7); p. 1704-1711 (Abstract only), Apr. 1995.
Walker, F. J.; Thromb. Res. vol. 22(3); p. 321-317 (Abstract only), 1981.

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