Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-08-07
2000-09-19
Eyler, Yvonne
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 723, 435810, 536 2433, C12Q 168, G01N 33574, C07H 2104
Patent
active
061209953
ABSTRACT:
A unique transcription product, CRCA-1, and alternative translation products generated thereform, are disclosed. The transcript and its translation products are markers for colorectal cells. Screening and diagnostic reagents, kits and methods for metastasized colorectal cancer are disclosed as are reagents, kits and methods for identifying adenocarcinomas as colorectal in origin. Compounds, compositions and methods of treating patients with metastasized colorectal cancer and for imaging metastasized colorectal tumors in vivo are disclosed. Compositions and methods for delivering active compounds such as gene therapeutics and antisense compounds to colorectal cells are disclosed. Vaccines compositions and methods of for treating and preventing metastasized colorectal cancer are disclosed.
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Barber Michael T.
Parkinson Scott J.
Pearlman Joshua M.
Schulz Stephanie
Waldman Scott A.
Eyler Yvonne
Thomas Jefferson University
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