Compositions that bind antiterminator RNA and assay for...

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Reexamination Certificate

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Reexamination Certificate

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07550511

ABSTRACT:
Compounds that are selective binding agents specific for RNA secondary and tertiary structures and a fluorescence assay for detecting the binding of small molecules to T-box antiterminator model mRNAs. The compounds include novel tri-substituted oxazolidinones and amino alcohols. The assay provides fluorescently labeled model mRNAs that include conserved sequence information typical of antiterminator bulge regions found in the mRNA of T-box gene regulatory systems.

REFERENCES:
patent: 202577 (1986-11-01), None
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