Compositions, probes and conjugates and uses thereof

Details Compositions, probes and conjugates and uses thereof Compositions, probes and conjugates and uses thereof

2011-08-23

2011-08-23

Riley, Jezia (Department: 1637)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S025300, C552S006000, C514S383000, C435S116000, C435S129000

Reexamination Certificate

active

08003771

ABSTRACT:
The present invention relates to compositions useful as probes and in other applications and methods of their use. In some embodiments, nucleotides are prepared and functionalized with dyes. In some embodiments a first molecule is functionalized with an alkynyl group, a second molecule is functionalized with an azide group, and said first and second molecules are mixed under conditions to form a conjugate with a 1,2,3-triazol group. In further embodiments, a nucleotide is functionalized with an alkynyl group, a dye is functionalized with an azide group, and mixing the nucleotide and the dye forms a conjugate capable of emitting light.

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