Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1994-07-18
1996-06-11
Criares, Theodore J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514649, 514654, 560 43, 560 45, 562433, 562445, A61K 31195, A61K 31135, C07C22900
Patent
active
055256317
ABSTRACT:
A composition which comprises a pharmaceutically acceptable carrier and an active ingredient, such active ingredient comprising L-DOPA ethyl ester derived from its crystaline form in an amount which is at least 97%, by weight, of the active ingredient, and L-DOPA in an amount which is less than 1% by weight of such active ingredient is provided by this invention. This invention also provides a process for preparing such a composition. Further, this invention provides a method of treating a patient suffering from Parkinson's disease which comprises administering to a patient a pharmaceutical composition comprising a therapeutically effective amount of L-DOPA ethyl ester derived from its crystaline form and a pharmaceutically acceptable carrier.
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Atlas Daphne
Melamed Eldad
Milman Isaac
Veinberg Alexander
Criares Theodore J.
Teva Pharmaceutical Industries Ltd.
The Yissum Research Development Company of the Hebrew University
White John P.
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