Compositions of p-hydroxybenzoic acid esters and methods of prep

Details Compositions of p-hydroxybenzoic acid esters and methods of prep Compositions of p-hydroxybenzoic acid esters and methods of prep

1983-09-12

1985-01-29

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514543, 548312, A01N 4350, A01N 3710

Patent

active

044965761

ABSTRACT:
A composition having broad spectrum antimicrobial activity and being freeze and heat stable is comprised of a clear solution containing up to approximately 90% by weight of a eutectic mixture of three or more lower alkyl esters of p-hydroxybenzoic acid such as isopropyl p-hydroxybenzoate, isobutyl p-hydroxybenzoate and n-butyl p-hydroxybenzoate in a ratio between approximately 1:1:1 to 4:2:2, respectively, approximately 10% to 90% by weight of a "Glydant" solution (composed of 55% 1,3-bis(hydroxymethyl)-5,5-dimethylhydantoin and 45% water) and at least approximately 0.5% by weight based on the weight of the eutectic mixture and the "Glydant" solution of an anionic surfactant. The latter, for example, may be dioctyl sodium sulfosuccinate, sodium lauryl sulfate or the ammonium or sodium salt of sulfated nonylphenoxypoly(ethyleneoxy) ethanol.

REFERENCES:
patent: 3097131 (1963-07-01), Ueno et al.
patent: 3960745 (1976-06-01), Billany et al.
patent: 3987184 (1976-10-01), Foelsch
patent: 4172140 (1979-10-01), Shull et al.
Chemical Abstracts, vol. 85, p. 86, (1976), Abst. No. 187144v.
Maeda et al., Agr. Biol. Chem., 40(9), 1705-1709, (1976).

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