Compositions of myeloid-cell-suppressive chemokines

Details Compositions of myeloid-cell-suppressive chemokines Compositions of myeloid-cell-suppressive chemokines

1992-12-09

2000-11-07

Achutamurthy, Ponnathapu

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

424 851, 514 2, 530300, A61K 3819, C07K 1452

Patent

active

06143289&

ABSTRACT:
Described are preferred processes for suppressing proliferation of or for myeloprotecting myeloid cells in mammals. The processes involve the use of chemokines of the group Macrophage Inflammatory Protein-2.alpha. (MIP-2.alpha.), Platelet Factor 4 (PF4), Interleukin-8 (IL-8) and Macrophage Chemotactic and Activating Factor (MCAF), or involve the use of these chemokines or Macrophage Inflammatory Protein-1.alpha. (MIP-1.alpha.) in synergistic combinations or while they are substantially completely in monomeric form (i.e. substantially free from their polymerized or aggregated forms).

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