Compositions of matter and methods of using same

Details Compositions of matter and methods of using same Compositions of matter and methods of using same

1986-07-28

1989-05-23

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514450, C07D49322

Patent

active

048332577

ABSTRACT:
New and exceptionally potent antineoplastic agents denominated Bryostatin 9, Bryostatin 10, Bryostatin 11, Bryostatin 12 and Bryostatin 13 have been isolated from the marine animal Bugula neritina (Linneaeus) (Bryozoan phylum) and the structures identified. Meaningful antineoplastic activity is found for each.

REFERENCES:
George R. Pettit et al, J. Am. Chem. Soc. (1984), vol. 106, pp. 6768-6771.
G. R. Pettit et al, Tetrahedron, vol. 41(16) (1985), pp. 985-994.

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