Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Reexamination Certificate
2006-08-29
2006-08-29
Henley, III, Raymond J. (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
C514S183000, C514S210020, C514S324000, C514S414000, C514S618000, C514S645000, C514S651000
Reexamination Certificate
active
07098198
ABSTRACT:
A method of prevention or treatment of a cholesterol-associated tumor is provided which comprises administering a therapeutically effective amount of an azetidinone-based cholesterol absorption inhibitor, preferably ezetimibe (SCH 58235) and/or its phenolic glucuronide, or at least one ezetimibe analog, e.g., SCH 48461 and SCH 58053, to a patient wherein the patient is either at risk of developing a cholesterol-associated tumor or already exhibits a cholesterol-associated tumor. Formulations of ezetimibe are also provided for the prevention or treatment of a cholesterol-associated tumor further comprising at least one other anticancer agent. An article of manufacture is also provided which comprises a container, instructions, and a composition, wherein the composition comprises a therapeutically effective amount of an azetidinone-based cholesterol absorption inhibitor, preferably ezetimibe or its phenolic glucuronide, and the instructions are for the administration of the composition for the prevention or treatment of a cholesterol-associated tumor.
REFERENCES:
patent: 6534540 (2003-03-01), Kindness et al.
patent: 2001/0041713 (2001-11-01), Waldstreicher et al.
patent: WO 93/02048 (1993-02-01), None
patent: WO 94/17038 (1994-08-01), None
patent: WO 95/08532 (1995-03-01), None
Webster's II New Riverside University Dictionary, published 1984, see pp. 933 and 1208.
Hawk et al., Primary Cancer Prevention Trails, Hematology/Oncology Clinics of North America, vol. 14, No. 4, Aug. 2000, pp. 809-830.
Schaffner Carl P.
Solomon Keith R.
Fox Rothschild LLP
Henley III Raymond J.
Karykion Inc.
LandOfFree
Compositions of ezetimibe and methods for the treatment of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions of ezetimibe and methods for the treatment of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions of ezetimibe and methods for the treatment of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3633341