Compositions of descarboethoxyloratadine

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S093000

Reexamination Certificate

active

09039260

ABSTRACT:
Methods are disclosed utilizing DCL, a metabolic derivative of loratadine, for the treatment of allergic rhinitis, and other disorders, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines.

REFERENCES:
patent: 3536809 (1970-10-01), Applezweig
patent: 3598123 (1971-08-01), Zaffaroni
patent: 3940485 (1976-02-01), Levinson et al.
patent: 4008796 (1977-02-01), Aylon
patent: 4282233 (1981-08-01), Vilani
patent: 4371516 (1983-02-01), Gregory et al.
patent: 4659716 (1987-04-01), Villani et al.
patent: 4777170 (1988-10-01), Heinrich
patent: 4990535 (1991-02-01), Cho et al.
patent: 5019591 (1991-05-01), Gardner et al.
patent: 5089496 (1992-02-01), Piwinski et al.
patent: 5100675 (1992-03-01), Cho et al.
patent: 5314697 (1994-05-01), Kwan et al.
patent: 5595997 (1997-01-01), Aberg et al.
patent: 5714501 (1998-02-01), Timmerman et al.
patent: 5731319 (1998-03-01), Aberg et al.
patent: 5900421 (1999-05-01), Handley et al.
patent: 0 288 640 (1988-11-01), None
patent: 0780127 (1997-06-01), None
patent: 396404 (2004-07-01), None
patent: WO 85/03707 (1985-08-01), None
patent: WO 92/11034 (1992-07-01), None
patent: WO 92/00293 (1992-09-01), None
patent: WO 92/20377 (1992-11-01), None
patent: WO 96/16641 (1996-06-01), None
patent: WO 96/20708 (1996-07-01), None
patent: WO 97/28797 (1997-08-01), None
patent: WO 99/32125 (1999-07-01), None
Berkow et al. (eds.),The Merck Manual of Diagnosis and Therapy, 16th Edition, Merck Research Laboratories, Rahway, NJ, May 1992, only pp. 326-332 & 2345-2346 supplied.
Gennaro et al. (eds.),Remington's Pharmaceutical Sciences, 18th Edition, Mack Publishing Co., Easton, PA, 1990, only pp. 1097-1130 (Chs. 58-59) supplied.
Berkow et al.(eds.)(II),Merck Manual of Diagnosis and Therapy, 16th Edition, Merck & Co., Rahway, New Jersey, May 1992, additional pp. 324-325 and 2347 supplied to supplement instant reference R.
[R]Berkow et al. (eds.), The Merck Manual of Diagnosis and Therapy, 16th Edition, Merk Research Laboratories, Rahway, NJ, May 1992, only pp. 326-332 & 2345-2346 supplied.
(S) Gennaro et al. (eds.)(I), Remington's Pharmaceutical Sciences, 18th Edition, Mack Publishing Co., Easton, PA, 1990, only pp.. 1097-1131 (Chs. 58-59) supplied.
(T) Gennaro et al. (eds.)(II), Remington's Pharmaceutical Sciences, 18th Edition, Mack Publishing Co., Easton, PA, 1990, only pp. 784 amd 1302 supplied.
Notari et al. “Biopharmaceutics and pharmacokinetics” Marcel Dekker, p. 163-164 (1975).
Sepracor Mar. 2006, internet description.
Goldman et al. “Desloratadine:a once daily nonsedating . . . ” Formulary 36:329-39 (2001).
Petrin, A., 1974, “Motion Sickness and its Treatment”,Schweiz. Med.63:79-81.
Wood, C.D. et al., 1987, “Mechanisms of Antimotion Sickness Drugs”,Aviation, Space, and Envir.Med. pp. A262-A265. (Sep. 1987).
Goodman and Gilman's, 1996,The Pharmacological Basis of Therapeutics, 9th Ed. p. 148, 588-592.
Carmeliet, 1992, “Voltage- and Time-Dependent Block of the Delayed K+Current in Cardiac Myocytes by Dofetilide”, J. Pharmacol. Exper. Ther. 262:809-817 (Issue No. 2).
Lunde, I., 1990, “Antihistamines”, Side Effects of Drugs 14:135-138.
Dukes, M.N.G. et al., 1988, “Side Effects of Drugs Annual 12”, Elsevier Science Publishers B.V. pp. 142-143.
Ebert, W., 1977, “Soft Elastic Gelatin Capsules: A Unique Dosage Form”, Pharmaceutical Technology 1:44-50 (Oct. 1977).
McClintock et al., “Skin Reactions and Terfenadine,”New Zealand Medical Journal, 108: 208 (1995).
Michel et al., “Skin Reactions to Hydroxyzine,”Dept. of Dermatology of Caen, France, 26: 147-149 (1997).
Monroe, “Loratadine in the Treatment of Urticaria,”Clinical Therapeutics, 19: 232-242 (1997).
Parslew, “Wafarin Treatment of Chronic Idiopathic Urticaria and Angio-oedema, ”Clinical and Experimental Allergy, 30: 1161-1165 (2000).
Roquet et al., “Combined Antagonism of Leukotriene and Histamine Produces Predominanat Inhibition of Allergen-Induced Early and Late Phase Airway Obstruction in Asthmatics,”Am. J. Respir. Crit. Care Med., 155: 1856-1863 (1997).
Yap, “The Current Cardiac Safety Situation with Antihistamines,”Clinical and Experimental Allergy, 29(suppi. 1): 15-24(1999).

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