Compositions of and new uses for N-acylanilinobutyric acids

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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A61K 31195

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active

042050880

ABSTRACT:
Pharmaceutically-acceptable compositions containing, as an active ingredient, at least one N-acylanilinobutyric acid have uses unrelated to the choleretic activity suggested in U.S. Pat. No. 3,780,095. Moreover, the further uses generally involve administration of smaller doses than would be required to obtain a choleretic effect.
The new uses include: (a) increasing the gastrointestinal enzyme secretion and (b) tonicizing the cardiovascular system. The increase of the gastrointestinal enzyme secretion is applied in the treatment of different diseases, such as treatment of sprue, treatment of indigestion, treatment of acute and chronic pancreatitis, therapy for degenerated intestine mucous membrane, treatment of stomach spasms, treatment of stomach ulcers, treatment of diseases where the application of an antigastrin is indicated. The tonicising of the cardiovascular system is applied in, e.g., increasing the circulation of blood in internal organs, increasing the heart force, treating disturbances in the liver function.

REFERENCES:
patent: 3780095 (1973-12-01), Klemm
PDR (1968) pp. 648, 771, 828, 948, 1138 & 1149.

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