Compositions of active Wnt protein

Details Compositions of active Wnt protein Compositions of active Wnt protein

2006-12-26

2006-12-26

Chism, B. Dell (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S002600, C530S326000, C530S344000, C435S383000

Reexamination Certificate

active

07153832

ABSTRACT:
Compositions of purified biologically active Wnt proteins are provided. Wnt proteins are found to be hydrophobic and post-translationally modified by addition of a lipid moiety at a conserved cysteine residue. Methods for isolation of Wnt utilize detergents that maintain the solubility of the modified protein.

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Genbank accession: AK013218.
Genbank accession: NP—003382.1.
Genbank accession: NP—003383.1.
Genbank accession: NP—003384.1.
Genbank accession: NP—003385.2.
Genbank accession: NP—003386.1.
Genbank accession: NP—003387.1.
Genbank accession: NP—004176.2.
Genbank accession: NP—004616.2.
Genbank accession: NP—004617.2.
Genbank accession: NP—005421.1.
Genbank accession: NP—006513.1.
Genbank accession: NP—057171.2.
Genbank accession: NP—078613.1.
Genbank accession: NP—079492.2.
Genbank accession: NP—110380.1.
Genbank accession: NP—110388.2.
Genbank accession: NP—114139.1.
Genbank accession: NP—476509.1.
Genbank accession: NP—478679.1.
Genbank accession: NP—490645.1.
Genbank accession: X56842.
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Van Leeuwen et al., Biological Activity of Soluble Wingless Protein in Cultured Drosophila Imaginal Disc Cells, Nature, 1994, 24:368(6469):342-4.

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