Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1986-02-03
1987-05-26
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
A61K 3156
Patent
active
046686681
ABSTRACT:
A compound of the formula ##STR1## wherein Z is alkoxy of 1-4 carbon atoms and Y is amino, inhibits the growth of murine ductal carcinoma (MXT mammary tumors). A compound wherein Z is OH and Y is nitro, administered orally, inhibits the growth of MXT mammary tumors.
REFERENCES:
patent: 3377362 (1968-04-01), Cantrall et al.
patent: 3526648 (1970-09-01), Bertin et al.
patent: 4340602 (1982-07-01), Brooks
patent: 4496555 (1985-01-01), Brooks et al.
patent: 4522758 (1985-06-01), Ward et al.
Rozhin et al, "Proc. Am. Assoc. Cancer Research", No. 21 (1980), p. 260.
Rozhin et al, Cancer Res., 43:2611-2617 (Jun., 1983).
Neeman et al, J. Med. Chem., 1983:465-469 (1983).
Utne et al, J. Org. Chem., 33:2469-2473 (1968).
Iyer et al, J. Org. Chem., 47:644 (1982).
Iyer et al, J. Med. Chem., 28:162 (1983).
Brooks et al, J. Toxic. and Environ. Health, 4:283-300 (1978).
Rozhin et al, J. Biol. Chem., 252:7214-7220 (1977).
Pack et al, Endocrinology, 95:1680-1690 (1974).
Brooks Samuel C.
Horwitz Jerome P.
Lipovsky Joseph A.
Roberts, Jr. John S.
Schenkman Leonard
Wayne State University
LandOfFree
Compositions inhibiting murine MXT ductal carcinoma does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions inhibiting murine MXT ductal carcinoma, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions inhibiting murine MXT ductal carcinoma will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-703932