Compositions incorporating a salt of monoester of citric acid an

Details Compositions incorporating a salt of monoester of citric acid an Compositions incorporating a salt of monoester of citric acid an

1989-07-07

1992-02-18

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic nonactive ingredient containing other...

Carboxylic acid ester

A61K 4700

Patent

active

050895311

ABSTRACT:
A skin treatment composition comprising a physiologically acceptable carrier and 1-35% by weight of a salt of a monoester of citric acid. The skin treatment composition imparts a pleasant smoothness to the skin and may be incorporated in several products to treat skin dryness. The hydrophobic group having an ester linkage to citric acid has 10 to 18 carbon atoms. Monoester of citric acid may be synthesized with low levels of di- and triester by forming citric acid anhydride and reacting this to form the monoester.

REFERENCES:
patent: 4673525 (1987-06-01), Small et al.
patent: 4695395 (1987-08-01), Caswell et al.
patent: 4866203 (1989-09-01), Weil
Chem. Abst., 93:31633h (1980) Oppenlaender et al.

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