Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Reexamination Certificate
2011-04-19
2011-04-19
Fronda, Christian L (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
C435S183000, C435S002000, C435S252300, C435S320100, C536S023200
Reexamination Certificate
active
07927851
ABSTRACT:
The present invention relates to nucleotide sequences encoding ent-kaurenoic acid 13-hydroxylase polypeptides and polypeptides having ent-kaurenoic acid 13-hydroxylase activity. The invention also relates to methods of producing steviol and steviol glycosides.
REFERENCES:
patent: 3-277275 (1991-12-01), None
Chica et al. Curr Opin Biotechnol. Aug. 2005;16(4):378-84.
Sen et al. Appl Biochem Biotechnol. Dec. 2007;143(3):212-23.
Accession A7NTM1, published Oct. 2, 2007.
Brandle, J. E., et al., “Leaf ESTs fromStevia rebaudiana: A Resource for Gene Discovery in Diterpene Synthesis”,Plant Molecular Biology, 50, (2002), 613-622.
Brandle, J. E., et al., “Steviol Glycoside Biosynthesis”,Phytochemistry, 68, (2007), 1855-1863.
Geuns, J. M., “Molecules of Interest—Stevioside”,Phytochemistry, 64, (2003),913-921.
Humphrey, T. V., et al., “Spatial Organisation of Four Enzymes fromStevia rebaudianathat are Involved in Steviol Glycoside Synthesis”,Plant Molecular Biology, 61, (2006), 47-62.
Imler, S., et al., “Indole Alkaloid Biosynthesis inCatharanthus roseaus: New Enzyme Activities and Identification of Cytochrome P450 CYP72A1 as Secologanin Synthase”,The Plant Journal, 24(6), (2000),797-804.
Jennewein, S., et al., “Taxol Biosythesis: Taxane 13α-Hydroxylase is a Cytochrome P450-Dependent Monooxygenase”,Proc. Natl. Acad. Sci. USA, 98(24), (2001), 13595-13600.
Kim, K. K., et al., “Hydroxylation ofent-Kaurenoic Acid to Steviol inStevia rebaudianaBertoni—Purification and Partial Characterization of the Enzyme”,Archives of Biochemistry and Biophysics, 332(2), (1996), 223-230.
Nelson, D. R., et al., “P450 Superfamily: Update on New Sequences, Gene Mappin, Accession Numbers and Nomenclature”,Pharmacogenetics, 6, (1996),1-42.
Pompon, D., et al., “[6] Yeast Expression of Animal and Plant P450s in Optimized Redox Environments”,Methods of Enzymology, 272, (1996),51-64.
Richman, A., et al., “Functional Genomics Uncovers Three Glucosyltransferases Involved in the Snythesis of the Major Sweet Glucosides ofStevia rebaudiana”, The Plant Journal, 41, (2005),56-67.
Brandle Jim
Richman Alex
Fronda Christian L
Remenick PLLC
Vineland Research and Innovation Centre
LandOfFree
Compositions having ent-kaurenoic acid 13-hydroxylase... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions having ent-kaurenoic acid 13-hydroxylase..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions having ent-kaurenoic acid 13-hydroxylase... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2715176