Compositions having a physiological cooling effect

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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A61K 31045

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active

040693457

ABSTRACT:
Alkyl-substituted methanols are disclosed having the property of stimulating the cold receptors of the nervous system of the human body to produce a cold sensation and are used for this purpose in a variety of edible and topical preparations.

REFERENCES:
patent: 2001046 (1975-05-01), Welch
patent: 3511914 (1970-05-01), Wolkoff et al.
patent: 3644653 (1972-02-01), Tcheitcheff
Remington's Pharmaceutical Sciences, 13th Edition, (1965), p. 855.
Wilson et al., Textbook of Organic Medicinal and Pharmaceutical Chemistry, Fourth Edition, (1962), pp. 111-112.
Chemical Abstracts, Eighth Collective Index, (1967-1971), vols. 66-75, pp. 18623s-18627s.
Chemical Abstracts, Seventh Collective Index, (1962-1966), vols. 56-65, pp. 13780s-13782s.

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