Compositions for treatment or prevention of bioterrorism

Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid

Reexamination Certificate

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Details

C424S493000, C424S489000, C424S490000, C128S200140

Reexamination Certificate

active

06991779

ABSTRACT:
Compositions containing biologically active molecules encapsulated in self-assembling, diketopiperazine microspheres (TECHNOSPHEREs™) and methods for making and administering such compositions are described herein. The compositions can be used to immunize individuals against agents of biological warfare. The biologically active molecules include atropine, antibodies, antigens, and antibiotics. The compositions can be placed in an inhalation device for self-administration. Pulmonary delivery of TECHNOSPHERE™ encapsulated atropine, antibodies, vaccines, and antibiotics provides an accelerated onset of immunity to the targeted disease. Furthermore, the TECHNOSPHERE™ encapsulated atropine, antibodies, vaccines, and antibiotics are stable formulations, suitable for stockpiling, rapid dissemination and mass treatment.

REFERENCES:
patent: 5352461 (1994-10-01), Feldstein et al.
patent: 5503852 (1996-04-01), Steiner et al.
patent: 6071497 (2000-06-01), Steiner et al.
patent: 6253762 (2001-07-01), Britto
patent: 2002/0187984 (2002-12-01), Boyce et al.
Drug Information Handbook, (Lacy et al) 1993, pp. 81-82, Lexi-Comp,Inc.

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