Compositions for treating glaucoma containing a carbostyril

Details Compositions for treating glaucoma containing a carbostyril Compositions for treating glaucoma containing a carbostyril

1980-01-02

1982-01-05

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 3147

Patent

active

043094325

ABSTRACT:
This invention provides a glaucoma treating composition comprising at least one of carbostyril derivatives represented by the formula ##STR1## wherein R.sup.1 is hydrogen, lower alkyl or lower alkenyl, R.sup.2 is hydrogen or a group ##STR2## wherein R.sup.4 is lower alkyl, cycloalkyl, or lower alkyl substituted by phenyl with or without a lower alkoxy substituent on the phenyl nucleus, R.sup.3 is a group ##STR3## wherein R.sup.4 is as defined above when R.sup.2 is hydrogen, or R.sup.3 is hydrogen, hydroxyl, ureido, lower alkynyloxy, lower alkoxy having a lower alkanoyl substitutent, lower alkanoylamino or lower alkenyloxy when R.sup.2 is ##STR4## and the carbon-to-carbon bond between the 3-position and the 4-position of the carbostyril skeleton is a single bond or double bond, and pharmacologically acceptable acid addition salts thereof; and a method of treating glaucoma comprising administering said composition to a patient with glaucoma.

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patent: 4210753 (1980-07-01), Tominaga et al.
Brit. J. Ophthal. (1977), pp. 301-303--Bonomi et al.
Chem. Abst. 77, 775(w) (1972)-Pecori--Giraldi et al.
Chem. Abst. 81, 131,068(y) (1974)--Stankiewicz et al.
Chem. Abst. 82, 38754(e) (1975)--Sharaf et al.

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