Compositions for topical use having melanin synthesis-inhibiting

Details Compositions for topical use having melanin synthesis-inhibiting Compositions for topical use having melanin synthesis-inhibiting

1988-09-23

1991-02-05

Ore, Dale R.

Drug, bio-affecting and body treating compositions

Topical sun or radiation screening, or tanning preparations

424 60, 424 62, 424 69, 514938, 514944, A61K 742, A61K 744, A61K 748

Patent

active

049903306

ABSTRACT:
Compositions for topical use having melanin synthesis-inhibiting activity comprising kojic acid or its esters and at least one compound selected from the group consisting of azelaic acid, tropolone, lipoic acid, sorbic acid, glucosamine, derivative of glucosamine, tunicamycin, deoxynojirimycin, glutathione, cystein, hydroquinone, derivative of hydroquinone, dehydroacetic acid, chelidonic acid and lipoamide. The compositions have excellent human skin-whitening effect and anti-suntan effect.

REFERENCES:
patent: 4136166 (1979-01-01), Barnett et al.
patent: 4278656 (1981-07-01), Nagai et al.
patent: 4369174 (1983-01-01), Nagai et al.
patent: 4696813 (1987-09-01), Higa
Yakurigaku et al, Chemical Abstracts, 1985, vol. 102, pp. 348, 12207k.
Chemical Abstracts, vol. 103 (153486h).
Chemical Abstracts, vol. 81 (41292n).
Patent Abstracts of Japan, vol. 10, No. 103.

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