Compositions for the treatment of chronic wounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514616, 514928, A61K 3116

Patent

active

061660841

ABSTRACT:
The present invention provides the use of N-acetyl cysteine and its pharmaceutically acceptable salts and derivatives, for the preparation of a composition for treatment or prophylaxis of chronic ulcers. In particular, the treatment of venous ulcers, diabetic ulcers and decubitis ulcers.

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Joao Batista Viana et al. Observacoes Preliminares Sobre a Aplicacao Da N-Acetil-L-Cisteina Nas Ulceras Cronicas Das Pernas. Rev. Med. Bras., vol. 29, No. 4, 1972, pp. 201-205, XP000606606.
Clinical and Experimental Dermatology 1992; 17:427-432, A.S.Salim University Department of Surgery at the Medical City, Baghdad, Iraq, Role of Sulphydryl-Containing Agents in the Management of Venous(Varicose) Ulceration. A New Approach.
World Journal of Surgery 15, 264-269, 1991, Aws S. Salim, Ph.D.(Surg.), F.R.C.S.Ed., F.R.C.S. Glasg., F.I.C.S., F.C.I.C.D., University Dept of Surgery, The Medical City, Baghdad, Iraq, Original Scientific Reports. The Role of Oxygen-Derived Free Radicals in the Management of Venous (Varicose) Ulceration: A New Approach.
Annales Pharmaceutiques Francaises, vol. 35, No. 9-10, 1977, A Quevauviller & L Vu Ngoc Huygen "Treatment of Cutaneous Burns Provoked by Hydrofluoric Acid in the Rat", pp. 365-370.
Journal of Investigative Dermatology, vol. 102, No. 6, 1994, G. Senaldi et al. "Protective Effect of N-Acetylcysteine in Hapten Induced Irritant and Contact Hypersensitivity Reactions:, pp. 934-937.

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