Compositions for the reversal and detoxification of...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

Reexamination Certificate

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C514S731000, C514S400000, C514S647000, C514S274000, C514S330000, C514S327000, C514S338000, C514S317000, C514S626000, C514S304000, C514S458000, C514S739000, C514S762000, C514S544000

Reexamination Certificate

active

07968124

ABSTRACT:
Methods of attenuating the toxic or medically undesirable effects of drugs and toxins in a human by administering to a human an injectable formulation comprised of a dispersion of particles comprised of reversed cubic or reversed hexagonal lyotropic liquid crystalline material. The particles absorb or adsorb or otherwise sequester and attenuate the effect of drugs and toxins, and may be used as a rescue or reversal agent, or as a prophylaxis. The invention is especially applicable in reversing adverse effects of local anesthetics inadvertently delivered systemically, and attenuating the therapeutic effects of general anesthetics in the course of treatment.

REFERENCES:
patent: 5922317 (1999-07-01), Kayar et al.
patent: 2005/0101621 (2005-05-01), Lipsky
patent: WO 01/22960 (2001-04-01), None
patent: WO 03/000236 (2003-01-01), None
patent: WO 03/106589 (2003-12-01), None
patent: WO 2005/034872 (2005-04-01), None

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