Compositions for stabilizing proteins for long term dry storage

Details Compositions for stabilizing proteins for long term dry storage Compositions for stabilizing proteins for long term dry storage

1994-02-22

1996-08-20

Knode, Marian C.

Chemistry: analytical and immunological testing

Composition for standardization, calibration, simulation,...

Preservative, buffer, anticoagulant or diluent

436 8, 436 15, 436 16, G01N 3100

Patent

active

055478735

ABSTRACT:
The invention relates to a composition for stabilizing proteins for long term dry storage and superior recovery of their native protein structure for extended reconstituted stability at 2.degree.-8.degree. C. The composition comprises: 1) a defibrinated sodium-free blood plasma, 2) a glass-forming sugar, 3) a serum albumin and/or a gelatin, and 4) a potassium salt. In another aspect, the present invention relates to a method for stabilizing a protein for long term dry storage using the above mentioned composition.

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