Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2005-04-12
2005-04-12
Li, Q. Janice (Department: 1632)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
C424S093100, C424S424000, C435S325000, C435S363000, C435S366000
Reexamination Certificate
active
06878383
ABSTRACT:
The invention provides a composition for promoting regeneration of tissue which has degenerated in a subject as a result of a disease or disorder and a method of using the composition is provided. The composition comprises a biodegradable acellular matrix, and passaged autologous fibroblasts substantially free of immunogenic proteins, e.g., culture medium serum-derived proteins, integrated within the matrix. Also provided is an injectable composition comprising an acellular filler material (e.g., any type of collagen) and passaged autologous fibroblasts substantially free of immunogenic proteins, e.g., culture medium serum-derived proteins, for correcting defects in skin, such as wrinkles or scars, and for augmenting tissue in the subject, particularly facial tissue.
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Boss, Jr. William K.
Marko Olga
Fish & Richardson P.C.
Isolagen Technologies, Inc.
Li Q. Janice
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