Compositions for preventing secondary cataracts

Details Compositions for preventing secondary cataracts Compositions for preventing secondary cataracts

1989-07-26

1991-10-08

Rosenbaum, C. Fred

Drug, bio-affecting and body treating compositions

Lymphokine

514912, 604 49, A61K 3900

Patent

active

050552910

ABSTRACT:
Novel methods and compositions are provided for preventing secondary cataracts. A cytotoxic agent is employed which is introduced into the anterior chamber of the eye to inhibit proliferation of remnant lens epithelial cells after extracapsular cataract extraction. Desirably a non-cytotoxic agent cross-reactive with the cytotoxic agent is introduced prior to introduction of the cytotoxic agent. The agents can be provided as kits.

REFERENCES:
patent: 4307082 (1981-12-01), Rosenberg
patent: 4340535 (1982-07-01), Voisin et al.
patent: 4342828 (1982-08-01), Takaku et al.
patent: 4349528 (1982-09-01), Koproyski
patent: 4363758 (1982-12-01), Musuho et al.
patent: 4379145 (1983-04-01), Masuho et al.
patent: 4432751 (1984-02-01), Emery et al.
patent: 4590071 (1986-05-01), Scannon et al.
patent: 4657930 (1987-04-01), Emery et al.
patent: 4661347 (1987-04-01), Muller-Eberhard et al.
patent: 4698420 (1985-02-01), Urnovitz
Campbell, Monoclonal Antibody Technology, pp. 16-25.
Olsnes et al.: Biochemistry, vol. 21, No.16, 1973, pp. 3121-3126.
Masuho et al.: Biochemical and Biophysical Research Communications, vol. 90, No. 1, 1979, pp. 320-326.
Blythman et al.: Nature, vol. 290, pp. 145-146, Mar. 12, 1981.
Youle et al., Proc. Natl. Sci., U.S.A., vol. 77, No. 9, pp. 5483-5486, Sep. 1980.
Gilliland et al.: Proc. Natl. Sci U.S.A., vol. 75, No. 11, pp. 5319-5323, Nov. 1978.
Szoka et al: Proc. Natl. Sci. U.S.A., vol. 75, No. 9, pp. 4194-4198, Sep. 1978.
Heath et al., Proc. Natl. Sci., U.S.A., vol. 80 pp. 1377-1381, Mar. 1983.
"Methotrexate-Anticollagen Conjugate Inhibits In Vitro Lens Cell Outgrowth" by Hansen et al., Investigative Ophthalmology & Visual Science (1987)28:1206-1209.
"Use of Immunotoxin to Inhibit Proliferating Human Corneal Endothelium" by Fulcher et al., Investigative Ophthalmology & Visual Science (1988)29:755-759.

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