Compositions for parenteral administration and...

Details Compositions for parenteral administration and... Compositions for parenteral administration and...

2007-05-22

2007-05-22

Woodward, Michael P. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S400000, C424S490000, C424S493000, C424S494000, C424S489000, C424S498000, C424S502000

Reexamination Certificate

active

10608507

ABSTRACT:
The present invention is directed to parenterally-administrable microparticles for providing sustained-release of a therapeutic agent in the body, where the microparticles include a polymeric core containing a therapeutically effective amount of a therapeutic agent disposed therein, a first film encapsulating the core, the first film prepared from a first biodegradable polymer soluble in an appropriate solvent therefore, and a second film encapsulating the core and the first film, the second film prepared from a biodegradable polymer soluble in an appropriate solvent therefore, wherein the first film is insoluble in the solvent used to prepare the second film, and to parenterally-administrable compositions containing such microparticles dispersed in a suitable carrier therefore.

REFERENCES:
patent: 4891223 (1990-01-01), Ambegaonkar et al.
patent: 5328697 (1994-07-01), Raman et al.
patent: 1 270 024 (2003-01-01), None
patent: 1 374 860 (2004-01-01), None
patent: 1 430 914 (2004-06-01), None

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