Compositions for organic synthesis on solid phase and methods of

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...

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528 10, C08F 800

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active

061471593

ABSTRACT:
A modified solid support for use in solid phase synthesis which comprises:
a solid support having a linker group extending therefrom having the general formula: ##STR1## wherein R.sub.1 and R.sub.2 are each independently selected from the group consisting of alkyl, cycloalkyl, aryl, alkoxy, aryloxy, fluorine, chlorine, iodine and bromine.

REFERENCES:
patent: 5663245 (1997-09-01), Kennedy et al.
patent: 5773512 (1998-06-01), Chenera et al.
patent: 5859277 (1999-01-01), Whitlock et al.
Muzafarov, A. et al., "Degradable Hyperbranched Poly(bis(undecenyloxy)methylsilane)s", Macromolecules, vol. 28, No. 24, Nov. 20, 1995, pp. 8444-8446.
Chenera, B. et al., "Protodetachable Arylsilane Polymer Linkages for Use in Solid Phase Organic Synthesis", J. Am. Chem. Soc., vol. 117 (1995), pp. 11999-12000.
Boehm, T. et al., "Development of a Novel Silyl Ether Linker for Solid-Phase Organic Synthesis", J. Org. Chem., vol. 61 (1996), pp. 6498-6499.
Maxson, K. et al., "Silicon-Containing Solid Support Linkers", ACS meeting, Aug. 25-29, 1996, 1 page.
Stranix, B. et al., "Functional Polymers fron (Vinyl)polystyrene. Recyclable Polymer-Supported Organosilicon Protecting Groups for Solid-Phase Synthesis", J. Org. Chem., vol. 62, (1997), pp. 6183-6186.
Farrall, M. et al., "Bromination and Lithiation: Two Important Steps in the Functionalization of Polystyrene Resins", J. Org. Chem., vol. 11, No. 21, (1976), pp. 3877-3882.
Plunkett, M. et al., "Silicon-Based Linker for Traceless Solid-Phase Synthesis", J. Org. Chem., vol. 60, (1995), pp. 6006-6007.
Hu, Y. et al., "Novel Polymer-Supported Trialkylsilanes and Their Use in Solid-Phase Organic Synthesis", J. Org. Chem., vol. 63, No. 13, (1998), pp. 4518-4521.
Newlander, K. et al., "Simple Silyl Linker for the Solid Phase Organic Synthesis of Aryl-Containing Molecules", J. Org. Chem., vol. 62, (1997), pp. 6726-6732.
Woolard, F. et al., "A Silicon Linker for Direct Loading of Aromatic Compounds to Supports. Traceless Synthesis of Pyridine-Based Tricyclics", J. Org. Chem., vol. 62, (1997), pp. 6102-6103.
Thompson, L. et al., "Synthesis and Applications of Small Molecule Libraries", Chem. Rev., vol. 96, (1996), pp. 555-600.

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