Compositions for mucosal delivery of agents

Details Compositions for mucosal delivery of agents Compositions for mucosal delivery of agents

2011-03-15

2011-03-15

Wax, Robert A (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

C514S002600, C514S008100

Reexamination Certificate

active

07906140

ABSTRACT:
Compositions and methods for mucosal delivery of agents are provided. The compositions are intended for administration to mucosal surface, such as oral and nasal mucosa. The compositions provided contain one or more mucoadhesive proteins and an agent to be delivered. Methods for delivery of agents using the compositions provided herein are also provided.

REFERENCES:
patent: 4740365 (1988-04-01), Yukimatsu et al.
patent: 4889720 (1989-12-01), Konishi
patent: 4900552 (1990-02-01), Sanvordeker et al.
patent: 4921706 (1990-05-01), Roberts et al.
patent: 5033252 (1991-07-01), Carter
patent: 5052558 (1991-10-01), Carter
patent: 5154924 (1992-10-01), Friden
patent: 5178878 (1993-01-01), Wehling et al.
patent: 5182107 (1993-01-01), Friden
patent: 5234957 (1993-08-01), Mantelle et al.
patent: 5298246 (1994-03-01), Yano et al.
patent: 5323907 (1994-06-01), Kalvelage
patent: 5527527 (1996-06-01), Friden
patent: 5620708 (1997-04-01), Amkraut et al.
patent: 5672683 (1997-09-01), Friden et al.
patent: 5702727 (1997-12-01), Amkraut et al.
patent: 5744155 (1998-04-01), Friedman et al.
patent: 5833988 (1998-11-01), Friden
patent: 5977307 (1999-11-01), Friden et al.
patent: 5993846 (1999-11-01), Friedman et al.
patent: 6071535 (2000-06-01), Hayward et al.
patent: 6329508 (2001-12-01), Friden
patent: 6383513 (2002-05-01), Watts et al.
patent: 6426362 (2002-07-01), Miller et al.
patent: 6475511 (2002-11-01), Gohlke et al.
patent: 6552024 (2003-04-01), Chen et al.
patent: 6638521 (2003-10-01), Dobrozsi et al.
patent: 6749863 (2004-06-01), Chang et al.
patent: 6905688 (2005-06-01), Rosen et al.
patent: 6926898 (2005-08-01), Rosen et al.
patent: 6946134 (2005-09-01), Rosen et al.
patent: 6994857 (2006-02-01), Rosen et al.
patent: 7179484 (2007-02-01), Singh
patent: 2003/0171267 (2003-09-01), Rosen et al.
patent: 2003/0219472 (2003-11-01), Pauletti et al.
patent: 2003/0221201 (2003-11-01), Prior et al.
patent: 2003/0226155 (2003-12-01), Sadeghi et al.
patent: 2004/0010134 (2004-01-01), Rosen et al.
patent: 2004/0023334 (2004-02-01), Prior
patent: 2004/0037809 (2004-02-01), Quay et al.
patent: 2004/0077540 (2004-04-01), Quay
patent: 2005/0196440 (2005-09-01), Masters et al.
patent: 2005/0197495 (2005-09-01), Naidu
patent: 2006/0084794 (2006-04-01), Rosen et al.
patent: 2006/0093594 (2006-05-01), Naidu
patent: 2229286 (1999-08-01), None
patent: 2006/009825 (2006-01-01), None
patent: WO 2009/117151 (2009-09-01), None
patent: WO 2009/117152 (2009-09-01), None
HandBook of Pharmaceutical Excipients, 1986 Ed. Lecithin, p. 165.
Almeida et al. “Nasal Delivery of Vaccines,” Journal of Drug Targeting 3, 456-467 (1996).
Ansel,Introduction to Pharmaceutical Dosage Forms, Fourth Edition, Philadelphia: Lea& Febiger, p. 126 (1985).
Budavari, et al.(Eds.)The Merck Index, 12th Edition, Whitehouse Station, N.J :Merck & Co., pp. THER-1 to THER-28 (1996).
Drug Delivery Technology, Alkaline Acidic Triggering Effectpamphlet,2 pages, Archimedes Laboratories, Inc., Sep. 2005.
Drug Delivery Technology, Pre-Clinical Abstract, Oral Pharmacokinetics of MAPED(Mucosa Adhesive Protein Engineered Drugs)Bound in Human Recombinant Insulin, 6 pages,Archimedes Laboratories, Inc., Sep. 2005.
Drug Delivery Technology, Undenatured Proteinpamphlet, 2 pages, Archimedes Laboratories, Inc., Sep. 2005.
Good, Surface free energy of solids and liquids: Thermodynamics, molecular forces, and structure Journal of Colloid and Interface Science, vol. 59, Issue 3, pp. 398-419 (1977).
Gu, et al. “Binding of Acrylic Polymers to Mucin/Epithelial Surfaces: Structure-Property Relationships,” Critical Reviews in Therapeutic Drug Carrier Systems 5(1): 21-67 (1988).
Lehr, et al., “Visualization studies of the mucoadhesive interface,” Journal of Controlled Release, 18:249-260 (1992).
Nogrady,Medicinal Chemistry A Biochemical Approach, New York: Oxford University Press, pp. 388-392 (1985).
Peppas & Buri, “Surface, Interfacial and Molecular Aspects of Polymer Bioadhesion on soft tissues,” Journal of Controlled Release, 2:257-275 (1985).
Ryan et al. “Immunomodulators and delivery systems for vaccination by mucosal routes” Trends in Biotechnology, vol. 19, No. 8, pp. 293-304. (2001).
Simoes et al., “Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides” Gene Ther. (11):1798-807 (1999).
Smart et al., “An in-vitro investigation of mucosa-adhesive materials for use in controlled drug delivery,” J. Pharm. Pharmacol. 36:295. (1984).
Smart et al., “In vitro techiniques for measuring mucoadhesion,” J. Pharm. Pharmacol. 34:70P (1982).
Tabor et al., “Surface forces and surface interactions” Journal of Colloid and Interface Science, vol. 58, Issue 1, pp. 2-13 (1977).
Oratropin-1™ Website Printout, found at: www.ibe-technology.com/oratropin.htm [retrieved on Jan. 20, 2006] [6 pages].
Ectotropin-6™ Website Printout, found at: www.ibe-technology.com/ectotropin.htm [retrieved on Jan. 20, 2006] [4 pages].
HexaTropin-6™ Website Printout, found at: www.ibe-technology.com/hexatropin.htm [retrieved on Jan. 20, 2006] [3 pages].
U.S. Appl. No. 60/527,962, filed Dec. 8, 2003, Masters et al.
Virun Improving Life Through Safe & Effective Oral Delivery found at: www.slideshare.net/virun/virun-improving-life-through-safe-effective-oral-delivery [accessed on May 11, 2009].
Wright, R., “Companies to watch—Nutraceuticals World,” at: www.nutraceuticalsworld.com/articles/2009/06/companies-to-watch, (2009) [accessed on Jun. 4, 2009].
U.S. Appl. No. 12/383,244, filed Mar. 20, 2009.
U.S. Appl. No. 12/383,241, filed Mar. 20, 2009.
U.S. Appl. No. 12/456,926, filed Jun. 23, 2009.
U.S. Appl. No. 12/583,209, filed Aug. 13, 2009.
An English language translation of a Chinese Examination Report, issued Mar. 1, 2010, in connection with corresponding Chinese Patent Application No. 200580028061.8.
Examination Report, issued Jul. 21, 2008, in connection with European Patent Application No. 05762240.9.
Office Action, issued Nov. 26, 2008, in connection with Chinese Patent Application No. 200580028061.8.
Examination Report, issued Dec. 3, 2008, in connection with Canadian Patent Application No. 2,578,709.

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