Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1996-12-20
2000-07-04
Criares, Theodore J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514114, A01N 4304, A01N 5700
Patent
active
060839201
ABSTRACT:
Compositions and methods for the modulation of aberrant inositol trisphosphate concentration in neurons is disclosed. Inositol trisphosphate stimulates an increase in intraneuronal calcium ion concentration which can, if unregulated, lead to acute neurotoxicities following such insults as brain seizures, and brain anoxia/ischemia; and lead to chronic neurotoxicities in such diseases as Alzheimer's disease, Huntington's disease, Parkinson's Disease, and amyotrophic lateral sclerosis. Inhibited inositol trisphosphate production results in aberrantly low calcium ion levels leading to neuronal apoptosis.
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Criares Theodore J.
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