Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Reexamination Certificate
2005-07-05
2005-07-05
Smith, Lynette R. F. (Department: 1645)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
C424S001110, C424S001170, C424S001290, C424S001530, C424S001570, C424S184100, C424S278100, C424S400000, C424S408000, C424S417000, C424S418000, C424S420000, C424S425000, C424S428000, C424S450000, C424S469000, C424S472000, C424S490000, C424S491000
Reexamination Certificate
active
06913767
ABSTRACT:
Methods and compositions are provided for the encapsulation of antigens in PLGA microspheres for use as vaccines. Such microspheres can also contain adjuvants. Mixtures of microspheres are provided which release antigen at desired intervals to provide boosts with antigen.
REFERENCES:
patent: 3565559 (1971-02-01), Sato et al.
patent: 3737337 (1973-06-01), Schnoring et al.
patent: 4293539 (1981-10-01), Ludwig et al.
patent: 4389330 (1983-06-01), Tice et al.
patent: 4524067 (1985-06-01), Arichi et al.
patent: 4568559 (1986-02-01), Nuwayser et al.
patent: 4637905 (1987-01-01), Gardner
patent: 4652441 (1987-03-01), Okada et al.
patent: 4675189 (1987-06-01), Kent et al.
patent: 4719246 (1988-01-01), Murdoch et al.
patent: 4728721 (1988-03-01), Yamamoto et al.
patent: 4767628 (1988-08-01), Hutchinson et al.
patent: 4849228 (1989-07-01), Yamamoto et al.
patent: 4897268 (1990-01-01), Tice et al.
patent: 4902515 (1990-02-01), Loomis et al.
patent: 4917893 (1990-04-01), Okada et al.
patent: 4919929 (1990-04-01), Beck et al.
patent: 4954298 (1990-09-01), Yamamoto et al.
patent: 4962091 (1990-10-01), Eppstein
patent: 4990336 (1991-02-01), Silvestri et al.
patent: 5008116 (1991-04-01), Cahn
patent: 5015476 (1991-05-01), Cochrum et al.
patent: 5057540 (1991-10-01), Kensil et al.
patent: 5068112 (1991-11-01), Samejima et al.
patent: 5075109 (1991-12-01), Tice et al.
patent: 5100669 (1992-03-01), Hyon et al.
patent: 5126147 (1992-06-01), Silvestri et al.
patent: 5198533 (1993-03-01), Schally et al.
patent: 5242686 (1993-09-01), Chu et al.
patent: 5348867 (1994-09-01), Georgiou et al.
patent: 5624612 (1997-04-01), Sewall et al.
patent: 5643605 (1997-07-01), Cleland et al.
patent: 5667808 (1997-09-01), Johnson et al.
patent: 266119 (1988-05-01), None
patent: 279688 (1988-08-01), None
patent: 333523 (1989-09-01), None
patent: 399843 (1990-11-01), None
patent: 442671 (1991-08-01), None
patent: WO 90/03984 (1990-04-01), None
patent: WO 90/09166 (1990-08-01), None
patent: WO 91/12882 (1991-09-01), None
patent: WO 91/15238 (1991-10-01), None
patent: WO 93/07861 (1993-04-01), None
Floy et al. “Design of Biodegradable Polymer Systems for Controlled Release of Bioactive Agents”, In: Polymeric Delivery Systems: Properties and Applications, MA El-Nokaly et al (eds). American Chemical Society, Washington DC, 1993.
Immunization Practices Advisory Committee, Clinical Pharmacy 8:839-851, 1981.
Jeggery et al. Pharmaceutical Research 10(3):362-8, (Mar. 1993).
Alonso et al. Pharmaceutical Research 10(7):945-953, 1993.
Sanders et al. J. Pharm. Sci 73(9):1294-1297, 1984.
Eldridge et al. Mol. Immunol 28(3):287-294, 1991.
Wang et al. J. Controlled Release 17:23-32, 1991.
Newman et al. AIDS Research and Human Retroviruses 8(8):1413-1418, 1992.
Arthur et al., “Challenge of chimpanzees (Pan troglodytes) immunized with human immunodeficiency virus envelope glycoprotein gp120”Journal of Virology63 (12): 5046-5053 (1989).
Berman et al., “Human Immunodeficiency virus type 1 challenge of chimpanzees immunized with recombinant envelope glycoprotein gp120”Proc. Natl. Acad. Sci. USA85(14): 5200-5204 (Jul. 1988).
Chang et al., “Biodegradable Semipermeable Microcapsules Containing Enzymes, Hormone, Vaccines, and Other Biologicals”J. Bioengineering1:25-32 (1976).
ChenScience262:980-981 (1993).
Cohen, J., “Jitters Jeopardize AIDS Vaccine Trials”Science262:980-981 (1993).
Cowsar et al., “Poly (lactide-co-glycolide) Microcapsules for Controlled Release of Steroids”Methods in Enzymology112 (Drug and Enzyme Targ) 101-116 (1985).
Eldridge et al., “Biodegradable and Biocompatible Poly (DL-lactide-Co-Glycolide) Microspheres as an Adjuvant for Staphylococcal Enterotoxin B Toxoid Which Enhances the Level of Toxin Neutralizing Antibodies”Infection and Immunity59(9):2978-86 (1991).
Eldridge et al., “Biodegradable Poly (DL-lactide-coglycolide) Microspheres”Res. Immunol.143(5) 557-63 (1992).
Esparza et al., “Parameters Affecting the Immunogenicity of Microencapsulated Tetanus Toxoid”Vaccine10(10): 714-720 (1992).
Glaser, V., “Solving the HIV Vaccine Puzzle: Questions Still Outnumber the Answers”Genetic Engineering Newspps. 15-30 (Nov. 1, 1993).
Hora, et al., “Release of Human Serum Albumin from Poly(lactide-co-glycolide) Microspheres”Pharmaceutical Research7(11):1190-1194 (1990).
Hu et al., “Effect of immunization with a vaccinia-HIV env recombinant on HIV infection of chimpanzees”Nature328 (6132):721-723 (Aug. 1987).
Kensil et al., “Development of a genetically engineered vaccine against feline leukemia virus infection”J. Amer. Veterinary Med. Assoc.199(10):1423-1427 (1991).
Kohn et al., “Single Step Immunization Using a Controlled Release, Biodegradable Polymer With Sustained Adjuvant Activity”J. Immun. Methods95:31-38 (1986).
Maulding, “Prolonged Delivery of Peptides by Microcapsules”J. of Controlled Release6:167-176 (1987).
Nellore et al., “Evaluation of Biodegradable Microspheres as Vaccine Adjuvant for Hepatitis B Surface Antigen”Journal of Parenteral Science & Technology,vol. 46, No. 5: 176-180 (Sep.-Oct. 1992).
O'Hagan et al., “Biodegradable Microparticles as Controlled Release Antigen Delivery System”Immunology73(2):239-242 (1991).
Payne et al., “Water Soluble Phosphazene Polymers for Parenteral and Mucosal Vaccine Delivery”Vaccine Design: The Subunit Adjuvant Approach,Powell et al., New York, NY: Plenum Press vol. 6:473-493 (1995).
Preis, “A Single-step Immunization by Sustained Antigen Release”J. Immun. Methods28:193-197 (1979).
Putney, S., “How Antibodies Block HIV Infection: Paths to an AIDS Vaccine”TIBS17:191-196 (1992).
Singh et al., “Controlled Delivery of Diptheria Toxoid Using Biodegradable Poly (D,L lactide) Microcapsules”Pharmaceutical Research8(7): 958-961 (1991).
Tabata et al., “Activation of Macrophage in Vitro to Acquire Antitumor Activity by a Muramyl Dipeptide Derivative Encapsulated in Microspheres Composed of Lactide Copolymer”Journal of Controlled Release6:189-204 (1987).
Watts et al., “Microencapsulation Using Emulsification/Solvent Evaporation: An Overview of Techniques and Applications”Critical Review in therapeutic Drug Carrier Systems,vol. 7, Issue 3: 235-259 (1990).
White et al., “A purified Saponin Acts as an Adjuvant for a T-independent Antigen”Immunobiology of Proteins and Peptides VI,M.Z. Atassi, New York:Plenum Press pps. 207-210 (1991).
Wu et al., “Saponin Adjuvant Enhancement of Antigen-Specific Immune Responses To An Experimental HIV-1 Vaccine”J. of Immuno.148(5):1519-1525 (1992).
Cleland Jeffrey L.
Lim Amy
Powell Michael Frank
Genentech Inc.
Haliday Emily M.
Hines J.
Quine Intellectual Property Law Group P.C.
Smith Lynette R. F.
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