Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-10-17
2008-12-09
Carlson, Karen Cochrane (Department: 1656)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C530S350000
Reexamination Certificate
active
07462461
ABSTRACT:
Disclosed are compositions and methods of treating a cytokine mediated diseases by inhibiting Sema7A and VLA-1 interaction.
REFERENCES:
patent: 5010175 (1991-04-01), Rutter et al.
patent: 5266684 (1993-11-01), Rutter et al.
patent: 5789650 (1998-08-01), Lonberg et al.
patent: 5798230 (1998-08-01), Bornkamm et al.
patent: WO 91/19813 (1991-12-01), None
patent: WO 92/02536 (1992-02-01), None
patent: WO 93/03172 (1993-02-01), None
patent: WO 03/080673 (2003-10-01), None
Kohler et at., 1975, Nature 256: 495-497, “Continuous Cultures of Fused Cells Secreting Antibody of Predefined Specificity”.
Boerner et al., 1991, J. Immunol. 147:86-95, “Production of Antigen-specific Human Monoclonal Antibodies from In Vitro-Primed Human Splenocytes”.
Persson et al., 1991, Proc. Nat. Acad. Sci. USA 88: 2432-2436, “Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning”.
Huang and Stollar, 1991, J. Immunol Methods 141:227-236, “Construction of representative immunoglobulin variable region CDNA libraries from human peripheral blood lymphocytes without in vitro stimulation”.
Hanayama R, Tanaka M, Miwa K, Shinohara A, Iwamatsu A, Nagata S (2002) Identification of a factor that links apoptotic cells to phagocytes. Nature 417 182-7.
Kolodkin, A. L., Matthes, D. J., and Goodman, C. S. (1993). The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules. Cell 75, 1389-1399.
Pasterkamp, R. J., and Kolodkin, A. L. (2003). Semaphorin junction: making tracks toward neural connectivity. Curr Opin Neurobiol 13, 79-89.
Kikutani, H., and Kumanogoh, A. (2003). Semaphorins in interactions between T cells and antigen-presenting cells. Nat Rev Immunol 3, 159-167.
Xu, X., Ng, S., Wu, Z. L., Nguyen, D., Hamburger, S., Seidel-Dugan, C., Ebens, A. and Luo, Y. (1998). Human semaphorin K1 is glycosylphosphatidylinositol-linked and defines a new subfamily of viral-related semaphorins. J Biol Chem 273, 22428-2234.
Tamagnone, L., Artigiani, S., Chen, H., He, Z., Ming, G. I., Song, H., Chedotal, A., Winberg, M. L., Goodman, C. S., Poo, M. et al. (1999). Plexins are a large family of receptors for transmembrane, secreted, and GPI-enchored semaphorins in vertebrates. Cell 99, 71-80.
Pasterkamp, R. J., Peschon, J. J., Spriggs, M. K., and Kolodkin, A. L. (2003). Semaphorin 7A promotes axon outgrowth through integrins and MAPKs. Nature 424, 398-405.
Kikutani Hitoshi
Kumanogoh Atsushi
Sugiyama Kenji
Boehringer Ingelheim International GmbH
Bottino Anthony P.
Carlson Karen Cochrane
Datlow Philip I.
Devlin Mary-Ellen M.
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