Compositions for inhibiting platelet aggregation

Details Compositions for inhibiting platelet aggregation Compositions for inhibiting platelet aggregation

1997-11-07

1999-10-26

Spivack, Phyllis G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 31445

Patent

active

059729678

ABSTRACT:
The invention is a pharmaceutical composition for intravenous administration to a patient comprising
a) a pharmaceutically effective amount of 2-S-(n-Butylsulfonylamino)-3-[4-(4-(piperidin-4-yl)butyloxy)phenyl]propion ic acid;
b) a pharmaceutically acceptable amount of a citrate buffer effective to provide a pH of between about 5 and 7; and
c) a pharmaceutically acceptable amount of a tonicity adjusting agent effective to make the formulation substantially isotonic with the osmotic pressure of the biological system of the patient.

REFERENCES:
patent: 5292756 (1994-03-01), Duggan et al.
"Remington's Pharmaceutical Sciences" 16 Edition, Mack Publishing Company, Easton, PA (1980) pp. 1488-1497.
"Handbook of Pharmaceutical Excipients" 2nd Edition, A. Wade and P. Weller, Eds., The Pharmaceutical Press, London (1994) pp. 123-125, 443-444 and 454-458.

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