Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-05-15
1999-10-12
Spivack, Phyllis G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 31445
Patent
active
059655810
ABSTRACT:
A composition is disclosed comprising about 0.25 mg/ml 2-S-(n-Butylsulfonylamino)-3 -[4-(4-(piperdin-4-yl)butyloxylphenyl]propionic acid, about 8 mg/ml sodium chloride, about 2.7 mg/ml sodium citrate dihydrate, about 0.16 mg/ml citric acid anhydrous, wherein the composition osmolality concentration is between about 250-310 mOsmol/kg and the pH is in the range of between 5.5-6.5.
REFERENCES:
patent: 5733919 (1998-03-01), Gelotte
"Remington's Pharmaceutical Sciences" 16 Edition, Mack Publishing Company, Easton, PA (1980) pp. 1488-1497.
"Handbook of Pharmaceutical Excipients" 2nd Edition, A. Wade and P. Weller, Eds., The Pharmaceutical Press, London (1994) pp. 123-125, 443-444 and 454-458.
Merck & Co. , Inc.
Parr Richard S.
Spivack Phyllis G.
Winokur Melvin
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