Compositions for inhibiting bone loss

Details Compositions for inhibiting bone loss Compositions for inhibiting bone loss

1996-03-28

1997-09-23

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514324, 514333, 514422, 514428, 514443, 514578, 514296, A61K 3144, A61K 31445, A61K 3140, A61K 31185

Patent

active

056705140

ABSTRACT:
The present invention provides methods of inhibiting bone loss in mammals via the administration to a mammal in need of such treatment an effective amount of a compound from a series of benzoquinolin-3-ones. Such compounds also are sequentially or concurrently coadministered with a bone antiresorptive agent or a bone anabolic agent.

REFERENCES:
patent: 5239075 (1993-08-01), Audia et al.
Anderson, et al., Proc. Natl. Acad. Sci. USA, 87:3640 (1990).
Anderson, et al., Nature, 354:159-61 (1991).
Matzkin, et al., Clinical Endocrinol., 37:432-436 (1992).

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