Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1999-04-12
2000-12-12
Reamer, James H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
A61K 3170
Patent
active
061599425
ABSTRACT:
Precursors of adenosine triphosphate are administered orally to increase intracellular ATP concentration as dietary supplements or for treatment of reduced energy availability resulting from strenuous physical activity, illness or trauma. Pentose sugars are administered individually, mixed into dry food or in solution. The preferred pentose is D-ribose, singly or combined with creatine, pyruvate, L-carnitine and/or vasodilating agents. Additionally, magnesium, electrolytes, fatty acids and hexose sugars can be used. The compositions and methods of this invention are especially beneficial to mammals having reduced energy availability or high energy demand.
REFERENCES:
patent: 4605644 (1986-08-01), Foker
patent: 4719201 (1988-01-01), Foker
patent: 4824660 (1989-04-01), Angello et al.
patent: 4871718 (1989-10-01), Carniglia
patent: 4920098 (1990-04-01), Cotter et al.
patent: 4968719 (1990-11-01), Brevetti
patent: 5114723 (1992-05-01), Stray-Gundersen
patent: 5292538 (1994-03-01), Paul et al.
patent: 5391550 (1995-02-01), Carniglia et al.
patent: 5707971 (1998-01-01), Fahy
patent: 5714515 (1998-02-01), Bunger
Gross, M., et al., "Ribose administration during exercise: effects on substrates and products of energy metabolism in healthy subjects and a patient with myoadenylate deaminase deficiency", Klinische Wochenshrift, 69 (4), pp. 151-155, (Feb. 26, 1991).
Mahoney, Jr., J.R., et al., "A comparison of different carbohydrates as substrates for the isolated working heart", Journal of Surgical Research, 47 (6), pp. 530-534, (1989).
Pliml, W., et al., "Effects of ribose on exercise-induced ischaemia in stable coronary artery disease", The Lancet, 340 (8818), pp. 507-510, (Aug. 29, 1992).
Schultis, K., et al., "Xylitol in metabolism during stress conditons", Medizin und Ernahrung, 11 (3), Jahrgang, pp. 59-63, (1970).
St. Cyr, J.A., et al., "Enhanced high energy phosphate recovery with ribose infusion after global myocardial ischemia in a canine model", Journal of Surgical Research, 46 (2), pp. 157-162, (Feb. 1989).
Tan, Z.T., et al., "Verapamil,ribose andadenine enhance resynthesis of postischemic myocardial ATP", Life Sciences, 55 (18), pp. PL 345-PL 349, (1994).
Wagner, D.R., et al., "Effects of oral ribose on muscle metabolism during bicycle ergometer in AMPD-deficient patients", Annals of Nutrition and Metabolism, 35 (5), pp. 397-302, (1991).
Zimmer, H.G., et al., "Ribose accelerates the repletion of the ATP pool during recovery from reversible ischemia of the rat myocardium", Journal of Molecular and Cellular Cardiology, 16 (9), pp. 863-866, (Sep. 1984).
Gross, M., et al., "Metabolism of D-Ribose Administered Continuously to Healthy Persons and to Patients with Myoadenylate Deaminase Deficiency", Klin Wochenschr, vol. 67, 1205-1213, (1989).
Tullson, P.C., et al., "Adenine Nucleotide Syntheses in Exercising and Endurance-trained Skeletal Muscle", Doc. No. 0363-5143/91, Copyright 1991, The American Physiological Society, C342-C347, (1991).
Tullson, P.C., et al., "IMP Metabolism in Human Skeletal Muscle After Exhaustive Exercise", Doc. No. 0161-7567/95, Copyright 1995, The American Physiological Society, 146-152, (1995).
Zollner, N., et al., "Myoadenylate Deaminase Deficiency: Successful Symptomatic Therapy by High Dose Oral Administration of Ribose", Klin Wochenschr, vol. 64, 1281-1290, (1986).
Angello, D.A., et al., "Recovery of Myocardial Function and Thallium 201 Redistribution Using Ribose", American Journal of Cardiac Imaging, 3 (4), pp. 256-265, (Dec. 1989).
Cyr John St.
Johnson Clarence A.
Bioenergy Inc.
Reamer James H.
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