Compositions for improving fertility

Details Compositions for improving fertility Compositions for improving fertility

2006-10-03

2006-10-03

Hui, San-Ming (Department: 1617)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

Reexamination Certificate

active

07115650

ABSTRACT:
Inhibitors of dipeptidyl peptidase IV and pharmaceutical compositions comprising these inhibitors are useful in the treatment of infertility, and particularly human female infertility due to polycystic ovary syndrome.

REFERENCES:
patent: 91/16339 (1991-10-01), None
patent: 93/08259 (1993-04-01), None
patent: 95/15309 (1995-06-01), None
patent: 98/19998 (1998-05-01), None
patent: 98/25644 (1998-06-01), None
Ashworth, D.M. et al. “2-Cyanopyrrolidides As Potent, Stable Inhibitors of Dipeptidyl Peptidase IV,”Biororg. Med. Chem. Lett.(1996), vol. 6, No. 10, pp. 1163-1166.
Bongers, J. “Kinetics of dipeptidyl peptidase IV proteolysis of growth hormone-releasing factor and analogs,”Biochem. Biophys. Acta.(1992), vol. 1122, No. 2, pp. 147-153.
Mentlein, R. “Dipeptidyl-peptidase IV (CD26)-role in the inactivation of regulatory peptides,”Regulatory Peptides(1999), vol. 85, No. 1, pp. 9-24.
Artini, P.G. et al. “Clinical Utility of Adjuvant Growth Hormone in the Treatment of Patients with Polycystic Ovaries Undergoing in Vitro Fertilization,”Journal of Assisted Reproduction and Genetics(1997), vol. 14, No. 1, pp. 4-7.
Lee, K.O. “Growth Hormone Treatment in Infertility: A Short Review,”Indian Journal of Pediatrics(1991), vol. 58, Suppl. No. 1, pp. 51-56.
Landolfi, L. et al. “Induzione Dell'Ovulazione Con Ormone Della Crescita E GnRH Nell' Ovaio Policistico,”Rassegna Internazionale Di Clinica E Terapia(1994), vol. 74, No. 12, pp. 529-532.

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